The role of tobacco in penile carcinoma

Journal  British Journal of Urology, Volume 75, Issue 3, Pages 375-377. March 1995.

Harish K; Ravi R

Department of Genito-urinary Surgery, Cancer Institute (WIA), Adyar, Madras, India.

Abstract


Objective:

To study the role of tobacco in squamous cell carcinoma of the penis.


Subjects and Methods:

The use of tobacco in the form of cigarettes, chewing tobacco and snuff was studied in a total of 503 patients and age-matched controls.


Results:

By multivariate analysis, a significant association was found between smoking (P = 0.002) or chewing tobacco (P < 0.001) and the use of snuff (P = 0.004) in patients with penile carcinoma as compared with controls. A dose-response relationship was observed for both smoking and chewing.


Conclusions:

The use of tobacco is a significant risk factor for penile carcinoma, and the use of more than one form of tobacco increases this risk.

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