British Journal of Urology, Volume 75, Issue 3, Pages 375-377. March 1995.
Department of Genito-urinary Surgery, Cancer Institute (WIA), Adyar, Madras, India.
To study the role of tobacco in squamous cell carcinoma of the penis.
The use of tobacco in the form of cigarettes, chewing tobacco and snuff was studied in a total of 503 patients and age-matched controls.
By multivariate analysis, a significant association was found between smoking (P = 0.002) or chewing tobacco (P < 0.001) and the use of snuff (P = 0.004) in patients with penile carcinoma as compared with controls. A dose-response relationship was observed for both smoking and chewing.
The use of tobacco is a significant risk factor for penile carcinoma, and the use of more than one form of tobacco increases this risk.
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